TY - JOUR T1 - Taurolidine as adjuvant treatment of relapsing peritonitis in peritoneal dialysis patients JO - Nefrología (English Edition) T2 - AU - Klimek,Kamila AU - Aresté Fosalba,Nuria AU - Ramírez López,Miguel Ángel AU - Gómez Castilla,Antonia Concepción AU - Salgueira Lazo,Mercedes SN - 20132514 M3 - 10.1016/j.nefroe.2020.03.003 DO - 10.1016/j.nefroe.2020.03.003 UR - https://www.revistanefrologia.com/en-taurolidine-as-adjuvant-treatment-relapsing-articulo-S2013251420300328 AB - Relapsing peritonitis in peritoneal dialysis patients is one of the complications that jeopardises the continuity of the technique. It is often associated with the formation of biofilm in the lumen of the catheter. To date, its removal remains the only recommended attitude. Due to its antimicrobial and antifungal properties, taurolidine has been previously used for the sealing of central line catheters and hemodialysis. Despite the good results obtained, there is no evidence available regarding its utility in peritoneal dialysis.This case report describes the use of taurolidine (TauroLock™ HEP 500) in 5 patients with relapsing peritonitis after antibiotic treatment completion. Mean follow-up for the detection of recurrences was 13.4 months. In 4 patients with infections caused by Staphylococcus epidermidis, eradication was achieved. In the remaining case, caused by Staphylococcus aureus, the taurolidine seal was ineffective and the removal of the catheter was required. ER -