OutcomeLong-term outcomeChanges in Quality of Life in Deceased Versus Living-Donor Kidney Transplantations
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Patients and Methods
Ninety-one patients underwent kidney transplantation in our hospital from January 2004 to December 2007. Eleven patients underwent cadaveric kidney transplantation (group DD) and 80 patients underwent living-donor kidney transplantation (group LD). Among the 11 cadaveric kidney transplantations, only 1 transplant was performed from a brain-dead donor, and the other 10 were performed from non–heart-beating donors (NHBDs). The background of the patients is presented in Table 1. The mean age was
Results
In group DD, although PCS was low (43.7), MCS was comparatively maintained (48.7) before transplantation. All specific domains were >40. After transplantation, PCS decreased to 35.3 at 1 year and 34.2 at 2 years. Specific domains physical functioning and role physical were decreased to levels <40. However, PCS increased to 52.6 at 3 years, which was higher than the pretransplantation level. Although MCS decreased to 43.2 at 1 year, it recovered to 52.2 at 2 years and 44.5 at 3 years (Fig 1).
In
Discussion
Kidney transplantation has been established as an ultimate therapy for the patients with an end-stage renal disease. The outcome of kidney transplantation, including patient and graft survival, has been improved to a satisfactory level worldwide. Also in Japan, the results of kidney transplantation have improved from year to year. Five-year patient and graft survivals of recipients who underwent living-donor kidney transplantation from 2000 to 2007 have been reached 95.9% and 90.7%,
Conclusions
The recipients of living-donor kidney transplantation showed an improvement in QOL immediately after transplantation, which was maintained for years. However, in the recipients of cadaveric kidney transplantation, physical QOL expressed by PCS decreased for 2 years after transplantation. The reasons seem to be the following: In Japan, recipients have to wait >14 years before undergoing kidney transplantation, owing to a shortage of donors, and therefore have various complications before
References (4)
Cited by (11)
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2022, Living Kidney Donation: a Practical GuideTrends and predictors of multidimensional health-related quality of life after living donor kidney transplantation
2020, Quality of Life Research