Journal Information
Vol. 37. Issue. 1.January - February 2017
Pages 1-114
Vol. 37. Issue. 1.January - February 2017
Pages 1-114
Letter to the Editor
Open Access
Reply to: «Sudden death in patients with advance chronic kidney disease»
Respuesta a la carta: «Muerte súbita en los pacientes con enfermedad renal crónica avanzada»
Francisco Caravaca
Servicio de Nefrología, Hospital Infanta Cristina, Badajoz, Spain
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Dear Editor,

We thank Dr. Sánchez Perales and Dr. Vázquez for their complimentary comments on our work and, with due respect, we feel we must give our reasons as to why the invaluable results from their study1 were not cited or mentioned in ours.

Our paper was written during the first half of 2014 and was accepted for publication in the journal Nefrología in the last quarter of that year. Due to problems related to a change of publisher and therefore outside the authors’ control, the paper was ‘stuck’ between publishers, until we were finally able to reactivate its publication – without modification – in April 2016.

We agree with Dr. Sánchez Perales and Dr. Vázquez in the difference to be expected in sudden death (SD) incidence rates depending on the criteria defining it. Perhaps a definition of SD that encompasses longer periods of development might have a greater epidemiological interest for examining the population's access to diagnostic and advanced treatment units for cardio- and/or neurovascular disease.

In addition to the results obtained in pre-dialysis patients, we have monitored also the progress of the 662 patients in the same group who started dialysis (data not published); Out of the 264 deaths (median: 27.7 months), 32 cases (12% of all deaths) were considered as SD. Thus, the SD incidence rate was 16.2 (95% CI: 11.5–22.9) cases per 1000 patient-years. This impact of SD on dialysis is similar to that observed by Dr. Sánchez Perales and Dr. Vázquez and it is significantly lower than that published on dialysis patients in other developed countries (19–153 cases × 1000 patient-years).2–5

These results illustrate the high quality of the renal replacement therapy we have in Spain.

E. Vázquez, C. Sánchez-Perales, F. García-García, M.J. García-Cortés, J. Torres, F. Borrego, et al.
Sudden death in incident dialysis patients.
Am J Nephrol, 39 (2014), pp. 331-336
C. Wanner, V. Krane, W. März, M. Olschewski, J.F. Mann, G. Ruf, et al.
Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis.
N Engl J Med, 353 (2005), pp. 238-248
R.S. Parekh, L.C. Plantinga, W.H. Kao, L.A. Meoni, B.G. Jaar, N.E. Fink, et al.
The association of sudden cardiac death with inflammation and other traditional risk factors.
Kidney Int, 74 (2008), pp. 1335-1342
S. Shastri, N. Tangri, H. Tighiouart, G.J. Beck, P. Vlagopoulos, D. Ornt, et al.
Predictors of sudden cardiac death: a competing risk approach in the hemodialysis study.
Clin J Am Soc Nephrol, 7 (2012), pp. 123-130
M. Jadoul, J. Thumma, D.S. Fuller, F. Tentori, Y. Li, H. Morgenstern, et al.
Modifiable practices associated with sudden death among hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study.
Clin J Am Soc Nephrol, 7 (2012), pp. 765-774

Please cite this article as: Caravaca F. Respuesta a la carta: «Muerte súbita en los pacientes con enfermedad renal crónica avanzada». Nefrologia. 2017;37:112–113.

Copyright © 2016. Sociedad Española de Nefrología
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