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Vol. 33. Núm. 2.Marzo 2013
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Vol. 33. Núm. 2.Marzo 2013
Páginas 0-288
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SureClick® (darbepoetina alfa) puede mejorar la satisfacción percibida y la competencia para el tratamiento de la anemia y aumentar la tasa de autoadministración en pacientes con enfermedad renal crónica no dializados
SureClick® (Darbepoetin alfa) can improve perceived satisfaction and competence for anemia treatment and increase self-administration in non-dialyzed patients with chronic kidney disease
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Grupo del Estudio PREFERENCE, Xavier Bonafontb, Ramón Romeroc, R.. Romerob, Isabel Martínezd, I.. Martíneze, María D. del Pinof, M.D.. del Pinog, José M. Gilh, J.M.. Gili, Pedro Arandaj, P.. Arandak, Ramón Rocal, J.. Claverolm, Joana Claveroln, M.. Cucalam, Mercedes Cucalan
b Hospital Germans Tr??as i Pujol, Badalona, Barcelona, Espa??a,
c Servicio de Nefrolog??a., Hospital Universitari Germans Tr??as i Pujol, Badalona, Barcelona, (Spain),
d Servicio de Nefrolog??a., Hospital Galdakao, Galdakao, Vizcaya, (Spain),
e Hospital Galdakao, Galdakao, Vizcaya, Espa??a,
f Servicio de Nefrolog??a., Hospital Torrec??rdenas, Almer??a, (Spain),
g Hospital Torrec??rdenas, Almer??a, Almer??a Espa??a,
h Servicio de Nefrolog??a., Hospital de Ja??n, (Spain),
i Hospital de Ja??n, Ja??n, Ja??n, Espa??a,
j Servicio de Nefrolog??a., Hospital Universitario Carlos Haya, M??laga (Spain),
k Hospital Carlos Haya, M??laga M??laga Espa??a,
l Servicio de Nefrolog??a., Hospital de Mollet, Barcelona, (Spain),
m Amgen S.A, Barcelona, Barcelona, Espa??a,
n Amgen S.A., Barcelona, (Spain),
Información del artículo

Antecedentes y objetivos: SureClick® es una pluma precargada para la administración de darbepoetina alfa (DA), que está lista para usar. Se exploró la satisfacción del paciente con SureClick® en comparación con las jeringas precargadas. Métodos: Estudio observacional multicéntrico, prospectivo, de 6 meses, en el que se incluyeron pacientes no dializados con enfermedad renal crónica (ERC) tratados con DA en jeringas precargadas que cambiaron a SureClick® al inicio del estudio. Las principales variables fueron: cambios en el Cuestionario de Satisfacción con el Tratamiento de la Anemia (ATSQ-S), Escala de Competencia Percibida en el Manejo de la Anemia (PCAS) y el porcentaje de autoadministración. Resultados: Se incluyeron 132 pacientes con una media (± desviación estándar [DE]) de 71,3 (14,6) años y un 57,6 % de mujeres. Las puntuaciones basales y finales medias (DE) en la ATSQ-S fueron, respectivamente, 25,5 (7,9) y 31,6 (4,9) (en una escala de 0 a 36-máxima satisfacción, cambio medio: 6,2, intervalo de confianza [IC] 95%: 4,6-7,8, p < 0,0001). La puntuación de la PCAS también aumentó significativamente (4,3 [2,0] vs. 5,6 [1,6], en una escala de 1 a 7-máxima competencia, p < 0,0001). Al inicio del estudio, el 47,7 % de los pacientes se autoadministraba DA con jeringas precargadas, frente al 74,2 % con SureClick® (p < 0,001). No hubo cambios significativos en el nivel medio de hemoglobina (11,4 [0,5] vs. 11,6 [1,3] g/dl, p = 0,193). Dos pacientes (1,5 %) presentaron reacciones adversas a SureClick® (dolor en el lugar de aplicación). Conclusiones: Los resultados sugieren que el cambio de jeringas precargadas a SureClick® podría aumentar la satisfacción del paciente y la percepción de la competencia en el manejo de la anemia en pacientes con ERC no dializados, y podría aumentar la tasa de autoadministración, lo que reduciría el uso de recursos sanitarios. 

Palabras clave:
Anemia
Palabras clave:
Competencia
Palabras clave:
Enfermedad renal crónica
Palabras clave:
Satisfacción
Palabras clave:
Darbepoetina alfa

Background and aims: SureClick® is a prefilled pen for administration of darbepoetin alfa (DA) that is ready-to-use. We explored patient satisfaction with SureClick® compared with prefilled syringes (PFS). Methods: Multicenter, prospective, 6-months, observational study in non-dialyzed patients with chronic kidney disease (CKD) treated with DA in PFS who switched to SureClick® at baseline. Main outcomes were: change in Anemia Treatment Satisfaction Questionnaire (ATSQ-S), Perceived Competence for Anemia Scale (PCAS) and self-administration rate. Results: We enrolled 132 patients with a mean(SD) age of 71.3 (14.6) years, 57.6% women. Mean(SD) ATSQ-S scores at baseline and final records were 25.5 (7.9) and 31.6 (4.9) (on a scale from 0 to 36 –maximum satisfaction-, mean change: 6.2, 95%CI: 4.6-7.8, p<0.0001). The PCAS also increased significantly (4.3 (2.0) vs 5.6 (1.6), on a scale from 1 to 7 –maximum competence, p<0.0001). At baseline 47.7% of patients self-administered DA with PFS, vs 74.2% with SureClick® (p<0.001). No significant changes in hemoglobin were observed (11.4 (0.5) vs 11.6 (1.3) g/dl, p=0.193). Two patients (1.5%) had adverse reactions to SureClick® (pain on application). Conclusions: Our results suggest that the change from PFS to SureClick® could increase patient satisfaction and perceived competence in anemia management in non-dialyzed CKD patients, and could increase the self-administration rate, thereby reducing use of health resources.

Keywords:
Anemia
Keywords:
Competence
Keywords:
Chronic kidney disease
Keywords:
Satisfaction
Keywords:
Darbepoetin alfa
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Nefrología

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